LOS ANGELES, CALIFORNIA: Emmy winner Christina Applegate, who was diagnosed with multiple sclerosis in 2021, continues to talk about the 'potential end' of her four-decade Hollywood career a month after admitting she would never act again on camera. In the third and final season of Netflix's 'Dead to Me', which premiered on November 17, she featured an admission from the 51-year-old resident of Hollywood that she found it difficult to watch herself.

'I was there, and I didn't want to relive it'

Applegate told Variety on Wednesday, "I could see the excruciating pain I was in every day I was there, and I didn't want to relive it. I had to take it in little tiny doses but I think it is a beautiful piece of work. I'm so grateful to [creator Liz Feldman] for seeing I had it in me. If this is my last job, thank God it was with [Linda Cardellini]."

'We don't know what my future as an actress is going to be'

Applegate, also an executive producer, had to ask sound guy Mitch Cohn to hold her knees firmly off-camera when MS made it impossible for her to stand in several situations. The breast cancer survivor said, "We don't know what my future as an actress is going to be." She added, "How can I handle it? How can I go onto a set and call the shots of what I need as far as my boundaries, physically? I don't know who is going to be as loving and understanding as this group of people were."

Christina was nominated for three Emmy Awards

Applegate was nominated for three Emmy Awards, three Critics' Choice TV Awards, a Golden Globe Award, four SAG Awards, and three SAG Awards for her portrayal of Jen Harding in the critically acclaimed drama. She gushed, "This is what I had always dreamed of doing. This just sat in a pocket inside my own soul that was very easy to access and portray," as per reports.

Jean Smart, a five-time Emmy winner who portrayed Applegate's on-screen mother in the ABC comedy 'Samantha Who?', will present Applegate with the TV Legacy Award at the Variety TV FYC Fest on Thursday at 1.40 pm at the 1 Hotel West Hollywood. Virtual tickets only cost $50, compared to limited in-person seats that cost between $399 and $599, as per reports.

The 'Don't Tell Mom the Babysitter's Dead' alum recalled, "It was the most fun I had ever had. 'Dead to Me' has that place in my heart now. 'But after Samantha Who?', I never thought I would have another experience like that ever again. The cast and the crew were sublime. The stars aligned and we were gifted this moment in time. When it was canceled [in 2009], I cried in bed for, like, a month."